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Pró-Fono Revista de Atualização Científica

versão impressa ISSN 0104-5687

Resumo

MATAS, Carla Gentile; SILVA, Sara Manami; MARCON, Bruna de Almeida  e  GONCALVES, Isabela Crivellaro. Electrophysiological manifestations in adults with HIV/AIDS submitted and not submitted to antiretroviral therapy. Pró-Fono R. Atual. Cient. [online]. 2010, vol.22, n.2, pp.107-112. ISSN 0104-5687.  http://dx.doi.org/10.1590/S0104-56872010000200007.

BACKGROUND: auditory evoked potentials (AEP) assess the neuroelectric activity on the auditory pathway -from the auditory nerve to the cerebral cortex - in response to an acoustic stimulus or event. Studies have demonstrated electrophysiological abnormalities in individuals with HIV/AIDS. AIM: to characterize the hearing electrophysiological manifestations in adults with HIV/AIDS by comparing the results obtained in the group exposed to antiretroviral therapy with those obtained in the group not exposed to such treatment. METHOD: electrophysiological evaluation of hearing (Auditory Brainstem Response - ABR, Auditory Middle Latency Reponse - AMLR and P300) was conducted in 56 individuals with HIV/AIDS: 24 participants composed group I (not exposed to antiretroviral treatment) and 32 participants composed group II (exposed to treatment). RESULTS: alterations in every AEP were observed in individuals with HIV/ AIDS, especially in the ABR. Indeed, the group exposed to antiretroviral treatment presented more alterations. CONCLUSION: individuals with HIV/AIDS may present alterations on the central and peripheral auditory nervous system. The group exposed to antiretroviral therapy presents more alterations on the brainstem auditory pathway.

Palavras-chave : HIV; Antiretroviral Therapy; Highly Active; Hearing; Evoked Potentials; Auditory.

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