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Brazilian Journal of Chemical Engineering

Print version ISSN 0104-6632On-line version ISSN 1678-4383

Abstract

BASTOS, R. G.; MOTTA, F. L.  and  SANTANA, M. H. A.. OXYGEN TRANSFER IN THE SOLID-STATE CULTIVATION OF D. monoceras ON POLYURETHANE FOAM AS AN INERT SUPPORT. Braz. J. Chem. Eng. [online]. 2016, vol.33, n.4, pp.793-799. ISSN 0104-6632.  http://dx.doi.org/10.1590/0104-6632.20160334s20150262.

In recent years, there has been a resurgence of interest concerning solid-state cultivation processes due to a number of advantages over submerged cultivation. However, studies on oxygen transfer and the performance of bioreactors are lacking. Processes that use inert supports loaded with chemically-defined liquid media have several potential applications and offer numerous advantages, such as improved process control and monitoring and enhanced process consistency compared with cultivation on natural solid substrates. The aim of this research was to study the oxygen transfer for the production of allergenic proteins from a biomass of Drechslera (Helminthosporium) monoceras cultured in a packed-bed reactor filled with polyurethane foam. The results show that a high protein concentration can be produced on an inert support with a high overall oxygen transfer coefficient (KLa) during cultivation.

Keywords : Solid-state cultivation; Drechslera (Helminthosporium) monoceras; Oxygen transfer; KLa; Inert support; Polyurethane foam.

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