Abstract
The solubility of 1-adamantanamine hydrochloride (1-AH) in ethanol, acetic acid, distilled water, N -methylpyrrolidone (NMP), N,N -dimethylformamide (DMF) and dimethylacetamide (DMAC) between 283.15 K and 333.15 K was measured using a laser monitoring observation technique. Results of these measurements were correlated with the NRTL equation and a semi-empirical equation. For six solvents studied, the data are well fitted with the two equations, which can be used as a useful model in the production process of 1-AH.
Keywords:
Solubility; 1-Adamantanamine hydrochloride; Modified Apelblat equation