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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
FREITAS, Thaís Helena Proença de and PROENCA, Nelson Guimarães. Chronic cutaneous Lupus erythematosus: study of 290 patients. An. Bras. Dermatol. [online]. 2003, vol.78, n.6, pp.703-712. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962003000600005.
BACKGROUND: Chronic cutaneous lupus erythematosus is a chronic inflammatory disease, which albeit relatively frequent, has been the object of few studies. OBJECTIVE: To characterize the epidemiological and clinical aspects of patients with chronic cutaneous lupus erythematosus, with a view to comparing the data obtained with the world literature. PATIENTS AND METHODS: A retrospective study was done on 290 patients with chronic cutaneous lupus erythematosus from 1982 to 1996, attended at the Dermatology Clinic of Hospital Santa Casa de Sao Paulo. RESULTS: The mean age at onset of the disease was 32.3 years, there was a female prevalence in relation to males (3.4:1), most of the patients had lesions located in the cephalic segment (58.3%). Regarding the clinical types, there was a prevalence of the typical discoid plaque in 90.4% of cases, followed by the verrucous or hypertrophic forms (7.9%), erythematous lupus pernio (1.4%) and tumid (0.3%). Lesions in the mucous membranes or transition epithelia occurred in 27.2% of the patients. CONCLUSIONS: Chronic cutaneous lupus erythematosus is a disease more frequent in adult women and the most common lesion is the typical discoid plaque. Mucous lesions occurred in approximately one fourth of the cases.
Keywords : lupus; lupus erythematosus; cutaneous; lupus erythematosus; discoid.