SciELO - Scientific Electronic Library Online

vol.79 issue3Evaluation of the side effects of acitretin on children with ichthyosis: a one-year study author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841


MARTINS, Gladys Aires  and  ARRUDA, Lucia. Systemic treatment of psoriasis - Part I: methotrexate and acitretin. An. Bras. Dermatol. [online]. 2004, vol.79, n.3, pp.263-278. ISSN 0365-0596.

The physiopathology of psoriasis has not yet been thoroughly clarified. Although there has been undeniable progress in the last decade, doubts remain about the nature of the antigens, which lead to activation of T lymphocytes, and about the regulation of the inflammatory mechanisms. Besides the development of new therapies, the improved management of classical systemic treatments has contributed to reduce the morbidity rate of the disease and has achieved a positive impact on the patients' quality of life. Underscoring the importance of this, the EMC-D article focuses on a review of using Methotrexate and Acitretin in the treatment of psoriasis. The use of biological therapies and other immunomodulators will be discussed in a future chapter.

Keywords : acitretin; methotrexate; psoriasis.

        · abstract in Portuguese     · text in English | Portuguese     · English ( pdf epdf ) | Portuguese ( pdf epdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License