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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
BELLET, Jane S. and PROSE, Neil S.. Vitiligo in children: a review of classification, hypotheses of pathogenesis and treatment. An. Bras. Dermatol. [online]. 2005, vol.80, n.6, pp. 631-636. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962005000700009.
Vitiligo is a relatively common dermatologic finding and one that has been observed since ancient times. Depigmentation of the skin, with loss of melanocytes on histology characterizes this disorder. A range of clinical phenotypes lead to varying degrees of morbidity. The cause of vitiligo remains unknown, although an autoimmune pathogenesis seems most likely. Treatment also remains difficult. A number of new therapies show significant potential. In this review, we will focus on the classification of childhood vitiligo, hypotheses of pathogenesis and treatment.
Keywords : Epidermis [transplantation]; PUVA therapy; Vitiligo.