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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
ALBUQUERQUE, Gabriella Corrêa de et al. Hereditary hemorrhagic telangiectasia: tranexamic acid for plantar ulcer. An. Bras. Dermatol. [online]. 2005, vol.80, suppl.3, pp. S373-S375. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962005001000019.
Case report of one patient with Hereditary Hemorrhagic Telangiectasia, also known as Rendu-Osler-Weber syndrome, treated with Tranexamic Acid for arteriovenous plantar ulcer. This drug has proved effective in controlling epistaxis, but the main point of this report is to expose the success use of this medication in the therapy of skin bleeding ulcer. The pathophysiologic and clinical features of the disease are reviewed and also the pharmacological aspects of the antifibrinolytic drugs. This drug was well tolerated by the patient and show evidence of good activity in the bleeding and healed the ulcer.
Keywords : Tranexamic acid; Telangiectasia, hereditary hemorrhagic; Foot ulcer.