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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
TRINDADE NETO, Pedro Bezerra da; SALES, Alexandre de Oliveira; SILVA, Aldavânea Cabral de Oliveira e and NUNES, Juliana Cristina Soares. Scleromyxedema: a case treated with oral prednisone. An. Bras. Dermatol. [online]. 2006, vol.81, n.1, pp. 55-58. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962006000100007.
Scleromyxedema is an idiopathic cutaneous mucinosis characterized by a papular eruption, skin induration and paraproteinemia. Histologically, fibrolast proliferation can be observed in the upper dermis associated with a mucine deposition. Treatment is difficult and at present there is no totally effective therapeutic modality to control the disease. The present report is on a 68-year-old patient with scleromyxedema without systemic manifestation, who responded to oral steroid therapy.
Keywords : Adrenal cortex hormones; Hyaluronic acid; Hypergammaglobulinemia; Mucinoses.