Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
MENDES, Wellington Luiz et al. Langerhans cell histiocytosis with nail involvement in childhood: a case report. An. Bras. Dermatol. [online]. 2006, vol.81, n.6, pp. 559-562. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962006000600007.
Langerhans cell histiocytosis may appear in a variety of ways. The authors present the case report of a 3-year-old white boy with a main complaint about chronic media otitis and a tumor lesion in right mastoid bone. Pathology revealed histiocytosis. The patient had severe dermatitis on the scalp and dystrophic changes with onycholysis, pustules, and nail plate deformity underneath all fingernails and toenails. These lesions responded to antineoplastic therapy. Development of nail dystrophics in Langerhans cell histiocytosis is unusual in children. This case suggests that treatment with antineoplastic therapy might be effective.
Keywords : Child; Langerhans cell histiocytosis; Langerhans cell histiocytosis [diagnosis]; Langerhans cell histiocytosis [therapy]; Nails; Nails [lesions].