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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
COELHO, Weber Soares; DINIZ, Lucia Martins and SOUZA FILHO, João Basílio de. Lichen sclerosus et atrophicus : report of two cases with atypical presentations. An. Bras. Dermatol. [online]. 2006, vol.81, suppl.3, pp.S297-S300. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962006000900010.
Lichen sclerosus et atrophicus is a chronic skin disease with multiple clinical presentations. It affects women, and less frequently men and children. The disease is usually located in the anal and genital regions. There is a strong association with autoimmune diseases, and immunogenetic studies demonstrated an association with HLA DQ7. The disease rarely affects extra-genital regions. The authors report two cases of lichen sclerosus et atrophicus in atypical locations (extra-genital), in which different management was used. High potency topical corticosteroid therapy is reported, with risks, however. Topical immunomodulating agents are described, obtaining favorable clinical responses and decreased risk of atrophy.
Keywords : Atrophy; Lichen sclerosus et atrophicus; Scleroderma, localized.