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Anais Brasileiros de Dermatologia

versão impressa ISSN 0365-0596versão On-line ISSN 1806-4841

Resumo

BATISTA, Mariana Dias et al. Bullous pyoderma gangrenosum and myelodysplastic syndrome. An. Bras. Dermatol. [online]. 2006, vol.81, suppl.3, pp.S309-S312. ISSN 1806-4841.  https://doi.org/10.1590/S0365-05962006000900013.

Pyoderma gangrenosum can present as a cutaneous manifestation of paraneoplastic syndromes. A case of bullous pyoderma gangrenosum associated with bicytopenia is described. During the complementary investigation, myelogram, bone marrow biopsy and karyotype were performed, and showed a pattern consistent with myelodysplastic syndrome. The patient was treated with dapsone with improvement. Pyoderma gangrenosum can be a manifestation of systemic diseases. The possibility of myelodysplastic syndrome should always be considered in patients with pyoderma gangrenosum associated with cytopenia. Pyoderma gangrenosum could indicate poorer prognosis in patients with systemic diseases.

Palavras-chave : Autoimmune diseases; Dapsone; Myelodysplastic syndromes; Pyoderma gangrenosum.

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