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vol.82 issue1Bullous systemic lupus erythematosus associated with lupus nephritis: report of two casesAtopic dermatitis: a cutaneous or systemic disease? The search for answers in the history of Dermatology author indexsubject indexarticles search
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Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841


FREITAS, Thais Helena Proença de  and  SOUZA, Daniella Abbruzzini Ferreira de. Systemic corticosteroids in dermatological practice. Part I : Main adverse effects. An. Bras. Dermatol. [online]. 2007, vol.82, n.1, pp.63-70. ISSN 0365-0596.

Systemic corticosteroids have been used in dermatological practice for approximately 60 years due to their anti-inflammatory and immunosuppressive effects. The challenge of corticosteroid therapy is to counterbalance the desirable actions and undesirable pharmacological effects. Unfortunately, advanced understanding of the mechanisms of action of corticosteroids has not resulted in the development of minimal toxicity regimens. In this article, we report the main pharmacological properties of systemic corticosteroids, their major indications in clinical practice and the adverse effects of high doses and/or prolonged administration.

Keywords : Adrenal insufficiency; Diabetes mellitus; Glucocorticoids; Glucocorticoids [adverse effects]; Hypertension; Osteonecrosis; Osteoporosis; Strongyloidiasis; Tuberculosis.

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