SciELO - Scientific Electronic Library Online

 
vol.82 issue2Treatment of american cutaneous leishmaniasisContact dermatitis in elderly patients author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841

Abstract

COSTA, Adilson; ALCHORNE, Maurício Mota Avelar; MICHALANY, Nilceo Schwery  and  LIMA, Hermênio Cavalcante. Acne vulgaris: a pilot study to assess an oral treatment with essential fatty acids using clinical, digital, and pathological analyses. An. Bras. Dermatol. [online]. 2007, vol.82, n.2, pp.129-134. ISSN 0365-0596.  http://dx.doi.org/10.1590/S0365-05962007000200003.

BACKGROUND: The relation among acne vulgaris, foods and treatment with essential fatty acids is unknown; however essential fatty acids are important in the pathophysiology of acne vulgaris. OBJECTIVES: To verify the clinical response of acne vulgaris with essential fatty acids and to establish the best methods to assess therapy. METHODS: Thirty-one volunteers took part in the study; in that, 16 (51.6%) received a product rich in essential fatty acids and 15 (48.4%) received a placebo. Clinical examination, volunteer's self-evaluation (subjective score), digital image and pathological evaluation were performed before and after treatment. RESULTS: There was no difference in the subjective score (p=0.419) and digital analysis (p=0.2187) between the product and placebo groups; there was a suggestive sign of improvement based on the pathological examination (p=0.087) but the chi-squared test showed no significance (¯2= 4.878); there was no statistical correlation between digital analysis and subjective score (p=0.127), between the subjective score and pathological examination (p=0.438). However, pathological and digital analyses showed correlation (p=0.012). CONCLUSIONS: 1) further studies with larger samples should be used to evaluate the clinical benefit; 2) self-evaluation and digital analysis were not sufficient to indicate the best therapeutic standard - product or placebo - for acne vulgaris; 3) the correlation between digital and pathological analyses seems to be the best form to assess quality of this therapy; 4) pathological examination seems to be the most sensitive method to evaluate this therapeutic regimen.

Keywords : Acne vulgaris; Fatty acids; essential; Linoleic acid.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf epdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License