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Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841


CASELLA, Erasmo Barbante et al. Acrodermatitis enteropathica-like eruption in two children with maple syrup urine disease. An. Bras. Dermatol. [online]. 2007, vol.82, n.2, pp.159-162. ISSN 0365-0596.

Acrodermatitis enteropathica-like cutaneous lesions have been reported in patients with some metabolic disorders that are treated with a low-protein diet. These patients usually have low blood levels of some amino acids, especially isoleucine. We describe two patients who evolved with eruptions resembling acrodermatitis enteropathica while undergoing treatment for maple syrup urine disease, without zinc deficiency. Isoleucine supplementation led to a prompt improvement of the skin disorder.

Keywords : Acrodermatitis; Isoleucine; Maple syrup urine disease.

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