SciELO - Scientific Electronic Library Online

 
vol.82 issue3Antihistaminic-induced gynecomastia in chronic urticaria treatmentBrittle nail syndrome author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841

Abstract

CHIMINAZZO, Mariana Discacciati et al. Bullous systemic lupus erythematosus in the childhood: case report. An. Bras. Dermatol. [online]. 2007, vol.82, n.3, pp.257-261. ISSN 0365-0596.  http://dx.doi.org/10.1590/S0365-05962007000300008.

We report a case of bullous systemic lupus erythematosus in a 9-year-old female, with a vesiculobullous eruption on the trunk, neck, genitals and limbs. A skin biopsy specimen showed subepidermal blister with neutrophils. Direct immunofluorescence revealed deposition of IgA, IgG, IgM and C3 at the epithelial basement membrane zone and indirect immunofluorescence was negative. Antinuclear antibodies and anti-Sm were positive. Resolution of the blisters occurred following treatment with dapsone and prednisone. This is a rare case of systemic lupus erythematous (SLE) in the childhood, whose initial manifestation was a bullous eruption. Bullous SLE should be considered in the differential diagnosis of children presenting with generalized bullous eruption.

Keywords : Blister; Child; Skin diseases, vesiculobullous; Lupus erythematosus, systemic.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf epdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License