Abstract

DALDON, Patrícia Érica Christofoletti  and  ARRUDA, Lúcia Helena Fávaro. Noninfectious granulomas: sarcoidosis. An. Bras. Dermatol. [online]. 2007, vol.82, n.6, pp. 559-571. ISSN 1806-4841.  http://dx.doi.org/10.1590/S0365-05962007000600010.

Sarcoidosis is a noninfectious granulomatous disease of unknown etiology, in which genetic, immunological, environmental and infectious factors seem to participate in the pathogenesis. Any organ or system can be affected with a wide range of clinical manifestations. As involvement of the skin occurs in approximately 20 to 35% of the cases, the dermatologist may play an important role in the diagnosis of the disease. Epidemiology, immunology and treatment are also discussed to provide a better understanding of this entity.

Keywords : Sarcoidosis; Sarcoidosis [diagnosis]; Sarcoidosis [epidemiology]; Sarcoidosis [etiology]; Sarcoidosis [genetic]; Sarcoidosis [immunology]; Sarcoidosis [mortality]; Sarcoidosis [pathology]; Sarcoidosis [therapy]; Skin manifestations.