Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
BONAMIGO, Renan Rangel; AULER, Alexandre; DURO, Kauê Marcolin and CARTELL, André. Scedosporium apiospermum infection and treatment with Voriconazole. An. Bras. Dermatol. [online]. 2007, vol.82, n.6, pp. 572-574. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962007000600011.
Infection by Scedosporium apiospermum may be severe when it affects immunosuppressed patients, circumstances under which diagnosis and treatment are difficult. The authors present the case of a diabetic patient using cyclosporine, methotrexate and systemic steroids to treat rheumatoid arthritis, who presented ulcers caused by S. apiospermum. After unsuccessful treatment with itraconazole, there was good response to voriconazole therapy. This drug represents a new alternative for the treatment of fungal infections.
Keywords : Immune tolerance; Itraconazole; Scedosporium.