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Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841


ORTIGOSA, Luciena Cegatto Martins  and  REIS, Vitor Manoel Silva dos. Dermatomyositis. An. Bras. Dermatol. [online]. 2008, vol.83, n.3, pp.247-259. ISSN 0365-0596.

Dermatomyositis is a chronic idiopathic inflammatory disorder that affects striated skeletal muscles, the skin, and other organs. Diagnostic criteria were established by Bohan & Peter and patients may be classified into five groups: juvenile dermatomyositis, primary dermatomyositis, amyopatic dermatomyositis, dermatomyositis associated with malignancies and dermatomyositis associated with other connective tissue disorders. Females are more affected and the mean age of diagnosis is 40 years. Skin manifestations are observed in all patients. Loss of proximal strength is the most common systemic alteration and lung involvement is most often manifested as interstitial pneumopathy. Neoplasms may be detected during the course of the disease specially in patients over 60. Lactic dehydrogenase serum levels are altered in the majority of cases and diagnosis can be established or the basis of skin and muscle biopsies and electroneuromiography. Corticosteroids are the first line drugs. The most common causes of death are malignant neoplasms, sepsis and pulmonary infection.

Keywords : Autoimmune diseases; Connective tissue diseases; Dermatomyositis [classification]; Dermatomyositis [diagnosis]; Dermatomyositis [etiology]; Dermatomyositis [therapy]; Muscular diseases.

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