Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
BONAMIGO, Renan Rangel; BAKOS, Lucio; CARTELL, André and EDELWEISS, Maria Isabel. Factors associated with rosacea in population samples of Southern Brazil: analysis of case-control studies. An. Bras. Dermatol. [online]. 2008, vol.83, n.5, pp.419-424. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962008000500004.
BACKGROUND: Rosacea is a dermatosis that has many factors associated with its onset. Most studies on this condition come from the United States and European countries, with little information produced and published about the disease in the Southern hemisphere, particularly in Brazil. OBJECTIVES: To describe the main clinical and histopathological factors associated with rosacea in population samples from southern Brazil. METHODS: Two case-control studies performed sequentially, with univariate and bivariate analysis, using p<0.05 for statistical significance (Chi-square test and Mantel-Haenzel, for stratifications) RESULTS: Rosacea is most frequent among women and in the age range of 40-50 years. Almost all cases have phototypes II and III. The inflammatory forms of rosacea are more often diagnosed than the vascular form and there is an association with serological positivity to Helicobacter pylori and with histopathological presence of Demodex folliculorum (p<0.05). Emotional and climatic changes, exposure to the sun and intake of alcoholic beverages were the main factors described as provoking or worsening the disease. CONCLUSIONS: We have obtained an overview of rosacea in a sample of the southern population of Brazil. While some data are similar to those already described internationally, other aspects, such as economic issues and the factors described as provoking or worsening the disease, are provided in greater detail.
Keywords : Helicobacter pylori; Helicobacter pylori [isolation & purification]; Rosacea; Rosacea [epidemiology]; Rosacea [etiology]; Rosacea [pathology].