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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
MALUF, Luciana Cirillo; BARROS, Jefferson Alfredo de and MACHADO FILHO, Carlos DAparecida dos Santos. Mastocytosis. An. Bras. Dermatol. [online]. 2009, vol.84, n.3, pp. 213-225. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962009000300002.
Mastocytosis is characterized by pathologic accumulation and activation of mast cells in tissues and organs. Although the classification for mastocytosis and diagnostic criteria are well accepted, there remains a need to define standards for the application of diagnostic tests, clinical evaluations, and responses to treatment. The objective of this article was to make an extensive literature review, providing comprehensive knowledge about the etiopathological and pathophysiological mechanisms, with a special emphasis on diagnosis, classification and treatment of mastocytosis, promoting continued medical education.
Keywords : Mastocytosis; Mastocytosis, cutaneous; Mastocytosis, systemic; Urticaria pigmentosa.