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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
MENDONCA, Ricardo José de and COUTINHO-NETTO, Joaquim. Cellular aspects of wound healing. An. Bras. Dermatol. [online]. 2009, vol.84, n.3, pp. 257-262. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962009000300007.
Wound healing is a dynamic interactive process that involves a sequence of molecular and cellular events. Recent advances in cellular and molecular biology have greatly expanded our understanding of the biological process involved in wound repair and tissue regeneration. From plasma extravasation, with coagulation and platelet aggregation, to reepithelialization and remodeling of injured tissue, the organism acts by trying to restore functionality tissue. Thus, the present study encompasses several cellular aspects involved in the wound healing process, as well as the main drugs used in treating the pathology related to wound healing complications. Economic aspects are also addressed, mainly related to chronic wounds of diabetic feet.
Keywords : Angiogenesis inducing agents; Capillary permeability; Wound healing.