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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
LANDIM, Fábio Machado et al. Cutaneous Rosai-Dorfman Disease. An. Bras. Dermatol. [online]. 2009, vol.84, n.3, pp. 275-278. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962009000300010.
Rosai-Dorfman disease is a self-limited benign disease. Rosai and Dorfman first described it in 1969, and the etiology of the disease remains unknown. Main manifestations are cervical adenopathy associated with fever, leukocytosis with neutrophilia and polyclonal gamaglobulinemia. Although the skin is the most common site of extra nodal disease, Rosai-Dorfman disease restricted to the skin is very rare with only a few cases described in the literature. This paper reports a rare case of cutaneous Rosai-Dorfman with skin as the sole site, and reviews the controversies of diagnosis and treatment.
Keywords : Histiocytosis; Non-langerhans-cell; Histiocytosis, sinus; Skin.