Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
FORTALEZA, Gleyce Tavares de Melo et al. Splenic tuberculosis during psoriasis treatment with infliximab. An. Bras. Dermatol. [online]. 2009, vol.84, n.4, pp. 420-424. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962009000400016.
Psoriasis is a chronic inflammatory disease affecting the skin and occasionally the joints. The biological agents have been engineered to target a specific step in the inflammatory cascade that leads to psoriasis, including tumor necrosis factor, which has a central role in the host defense against Mycobacterium tuberculosis. This is a case report about a psoriatic patient who presented splenic tuberculosis during treatment with infliximab.
Keywords : Psoriasis; Biological therapy; Tuberculosis.