Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
MOSQUEIRA, Carolina Balbi et al. Case for diagnosis. An. Bras. Dermatol. [online]. 2010, vol.85, n.1, pp.107-108. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962010000100019.
Langerhans cell histiocytosis is a rare disease of unknown cause, characterized by the proliferation of histiocytic cells (Langerhans cells). Its diagnosis is especially difficult due to its wide clinical spectrum, ranging from a single lesion to a multisystemic disorder. Diagnosis may be confirmed by means of an immunohistochemical study. Treatment depends upon the severity of the disease, and systemic chemotherapy may be needed.
Keywords : Histiocytes; Histiocytosis; Langerhans-Cell.