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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
AOKI, Valéria et al. Direct and indirect immunofluorescence. An. Bras. Dermatol. [online]. 2010, vol.85, n.4, pp.490-500. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962010000400010.
Immunofluorescence is a valuable auxiliary diagnostic tool for autoimmune bullous diseases and inflammatory disorders, since their clinical and histopathologic findings may be inconclusive. It is a feasible laboratory method that requires experienced technicians and detects in situ and circulating immune deposits that may be involved in the pathogenesis of such skin diseases.
Keywords : Autoimmunity; Basement membrane; Fluorescent antibody technique; Pemphigus.