Abstract

AOKI, Valéria et al. Direct and indirect immunofluorescence. An. Bras. Dermatol. [online]. 2010, vol.85, n.4, pp. 490-500. ISSN 0365-0596.  http://dx.doi.org/10.1590/S0365-05962010000400010.

Immunofluorescence is a valuable auxiliary diagnostic tool for autoimmune bullous diseases and inflammatory disorders, since their clinical and histopathologic findings may be inconclusive. It is a feasible laboratory method that requires experienced technicians and detects in situ and circulating immune deposits that may be involved in the pathogenesis of such skin diseases.

Keywords : Autoimmunity; Basement membrane; Fluorescent antibody technique; Pemphigus.