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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
SANCHEZ, Ana Paula Galli. Immunopathogenesis of psoriasis. An. Bras. Dermatol. [online]. 2010, vol.85, n.5, pp.747-749. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962010000500028.
Psoriasis is a common inflammatory disease affecting 1% of the Brazilian population. Th17 and Th1cells are involved with the immunopathogenisis of psoriasis. In this article it is discussed the interaction between the innate immunity (especially dendritic cells and keratinocytes) and adaptive immunity (T lymphocytes) in the pathogenesis of psoriasis.
Keywords : Allergy and immunology; Cytokines; T- lymphocytes; Psoriasis; Psoriasis [etiology].