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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
PEIXOTO, Isy; MAQUINE, Gustavo; FRANCESCONI, Valeska Albuquerque and FRANCESCONI, Fabio. Dermatophytosis caused by Tricophyton rubrum as an opportunistic infection in patients with Cushing disease. An. Bras. Dermatol. [online]. 2010, vol.85, n.6, pp.888-890. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962010000600017.
Trichophyton rubrum is a common agent found in superficial mycoses, which present ample nonin?ammatory lesions, with chronic evolution, especially in immunocompromised patients. The hypercortisolism in Cushing's syndrome increases the risk of infections as a result of the immunosuppressive effect of glucocorticoids. The reported cases here refer to two different types of dermatophytosis caused by Trichophyton rubrum in patients with Cushing's disease, resistant to antifungal treatment. The disease remitted after the levels of cortisol went back to normal.
Keywords : Cushing's syndrome; Dermatomycoses; Immunosuppression; Onychomycosis.