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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
MARTINS, Luis Eduardo Agner Machado and REIS, Vitor Manoel Silva dos. Immunopathology of allergic contact dermatitis. An. Bras. Dermatol. [online]. 2011, vol.86, n.3, pp.419-433. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962011000300001.
Allergic contact dermatitis is the consequence of an immune reaction mediated by T cells against low molecular weight chemicals known as haptens. It is a common condition that occurs in all races and age groups and affects the quality of life of those who present it. The immunological mechanism of this disease has been reviewed in recent decades with significant advance in its understanding. The metabolism and pathway of the haptens as well as the activation and mechanism of action of the cells responsible for both the immune reaction and its completion are discussed in this article
Keywords : Allergy and immunology; Dermatitis, allergic contact; Dermatitis, contact; Hypersensitivity.