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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
LESTRE, Sara Isabel Alcântara; GAMEIRO, Catarina Diogo; JOAO, Alexandre and LOPES, Maria João Paiva. Granulomas of the penis: a rare complication of intravesical therapy with Bacillus Calmette-Guerin. An. Bras. Dermatol. [online]. 2011, vol.86, n.4, pp.759-762. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962011000400021.
Immunotherapy with Bacillus Calmette-Guérin is widely used for treatment and prophylaxis of superficial urothelial cancer. Complications associated with Bacillus Calmette-Guérin treatment are common. The authors describe a case of granulomatous inflammation of the penis associated with intravesical Bacillus Calmette-Guérin therapy, presenting with multiple erythematous and painless nodules located on the glans. A review of the literature is also performed. Granulomatous balanoposthitis is a rare complication of Bacillus Calmette-Guérin immunotherapy, with heterogeneous clinical presentation, which can make the diagnosis difficult. Its clinical recognition is essential for early start of therapy with antitubercular agents and interruption of Bacillus Calmette-Guérin
Keywords : Administration, intravesical; Antitubercular Agents; Inflammation; Mycobacterium bovis; Penis.