SciELO - Scientific Electronic Library Online

 
vol.86 issue5Fundamentals of the knowledge about chemical additives present in rubber glovesHIV-associated tuberculous lymphadenitis: the importance of polymerase chain reaction (PCR) as a complementary tool for the diagnosis of tuberculosis - a study of 104 patients author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596

Abstract

TAGLIOLATTO, Sandra; ALCHORNE, Mauricio M. A  and  ENOKIHARA, Mauro. Sebaceous hyperplasia: a pilot study to correlate this skin disease with circulating androgen levels. An. Bras. Dermatol. [online]. 2011, vol.86, n.5, pp. 917-923. ISSN 0365-0596.  http://dx.doi.org/10.1590/S0365-05962011000500009.

BACKGROUND: The sebaceous glands are susceptible to the effects of androgens. A benign proliferation of these hormones, i.e. hyperplasia, occurs with age. OBJECTIVES: This was a pilot study to demonstrate whether any correlation exists between circulating androgen levels and an increase in the incidence of sebaceous hyperplasia. METHODS: Sixteen female patients with a diagnosis of sebaceous hyperplasia were compared to a control group of females of a similar age without the disease. Blood tests were performed on participants of both groups to measure circulating androgen levels (free and total testosterone and androstenedione levels). Results were tabulated for statistical analysis. RESULTS: These data showed no statistically significant differences in circulating androgen levels between the patients with sebaceous hyperplasia and the control group. CONCLUSION: These data suggest that no significant changes occur in circulating androgen levels [free and total testosterone, androstenedione, dehydroepiandrosterone (DHEA) and DHEA sulfate] in patients with sebaceous hyperplasia.

Keywords : Hormones; Hormones, hormone substitutes, and hormone antagonists; Hyperplasia; Sebaceous glands.

        · abstract in Portuguese     · text in English | Portuguese     · pdf in English | Portuguese