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Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
SOUZA JUNIOR, Januário de et al. Localized primary cutaneous nodular amyloidosis: case report. An. Bras. Dermatol. [online]. 2011, vol.86, n.5, pp.987-990. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962011000500018.
Amyloidosis results from deposition of fibrous and insoluble amyloid protein in extracellular spaces of organs and tissues. Amyloid deposition can be localized or systemic and either primary or secondary. We report a case of localized primary cutaneous nodular amyloidosis manifested by papular-nodular, reddish-brown lesions affecting the nasal area, without evidence of systemic involvement. Immunohistochemistry showed the presence of immunoglobulin kappa light chain.
Keywords : Amyloidosis; Plasma cells; Skin.