Anais Brasileiros de Dermatologia
Print version ISSN 0365-0596
On-line version ISSN 1806-4841
ROSMANINHO, Aristóteles et al. Diffuse plane xanthomatosis associated with monoclonal gammopathy. An. Bras. Dermatol. [online]. 2011, vol.86, n.4, suppl.1, pp.50-52. ISSN 0365-0596. http://dx.doi.org/10.1590/S0365-05962011000700012.
Diffuse plane normolipemic xanthomatosis (DPNX) is a rare, non-inherited disease that is often associated with systemic diseases, mainly malignant hematological (especially multiple myeloma) or lymph proliferative disorders. The DPNX can precede the appearance of such conditions by several years, so careful follow-up and periodic laboratory examinations are recommended even for patients that seemed to have no underlying disease. We describe a case associated with monoclonal gammopathy. This case shows that dermatological lesions can be the first manifestation of important hematological diseases and so physicians should be familiarized with this entity
Keywords : multiple Myeloma; Paraproteinemias; Xanthomatosis.