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vol.86 issue4  suppl.1Hyperkeratosis lenticularis perstansAcral lichen sclerosus et atrophicus: case report author indexsubject indexarticles search
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Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841


FERNANDES, Lana Bezerra et al. Langerhans cells histiocytosis with vulvar involvement and responding to thalidomide therapy: case report. An. Bras. Dermatol. [online]. 2011, vol.86, n.4, suppl.1, pp.78-81. ISSN 0365-0596.

Langerhans cell histiocytosis is a member of a group of rare histiocytic syndromes and is characterized for the proliferation of histiocytes called Langerhans'cells. Its manifestations vary from a solitary injury to systemic involvement, and vulvar lesions are uncommon. We describe a refractory case of cutaneous limited disease in a 57-year-old woman. She presented with a 6-year history of an erythematous papular eruption of the scalp, face, vulva, trunk and axillae. The diagnosis is difficult and in this case it was confirmed through immunohistochemical study and clinical improvement was achieved with thalidomide

Keywords : Histiocytes; Histiocytosis; Histiocytosis, Langerhans-cell.

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