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Anais Brasileiros de Dermatologia
Print version ISSN 0365-0596
TEIXEIRA, Talita Alves et al. Refractory endemic pemphigus foliaceous in adolescence successfully treated with intravenous immunoglobulin. An. Bras. Dermatol. [online]. 2011, vol.86, n.4, suppl.1, pp. 133-136. ISSN 0365-0596. http://dx.doi.org/10.1590/S0365-05962011000700035.
Endemic Pemphigus Foliaceous is a chronic autoimmune bullous skin disease. Treatment with prednisone often produces excellent results, but resistant forms exist, requiring alternative therapy. Alternative treatments have been used in cases of corticosteroid-refractory pemphigus, showing favorable results. This case study focuses on an adolescent male with a clinical-pathological diagnosis of pemphigus foliaceous with a severe clinical form of erythrodermis, unresponsive to multiple therapies, but which showed a satisfactory outcome with intravenous immunoglobulin. In this case we highlight the fact that the patient was a teenager who showed substantial clinical improvement as the result of using intravenous immunoglobulin, followed by complete remission after the fourth cycle of medication, allowing reduced doses of steroids and a consequent reduction of side effects
Keywords : Skin vesiculobullous; Intravenous immunoglobulins; Pemphigus.