SciELO - Scientific Electronic Library Online

 
vol.86 issue4  suppl.1Stiff skin syndrome: case reportMultiple facial angiofibromas treated with high-frequency equipment author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596

Abstract

HEIDRICH, Daiane et al. Successful treatment of terbinafine in a case of sporotrichosis. An. Bras. Dermatol. [online]. 2011, vol.86, n.4, suppl.1, pp. 182-185. ISSN 0365-0596.  http://dx.doi.org/10.1590/S0365-05962011000700047.

Sporotrichosis is a chronic subacute infection caused by fungi belonging to the Sporothrix Complex. In the present clinical case, nasal sporotrichosis was treated with potassium iodide. This was unsuccessful, and the treatment was restarted with a combination of potassium iodide and itraconazole. This however resulted in a further recurrence of the infection. The mycological cultures were tested in vitro for antifungal activity to assist in treatment. Terbinafine, an antifungal drug, produced the best results and was therefore used for the rest of the treatment course, with no recurrence after two years of its completion. In addition, both cultures were compared using RAPD and different fragment patterns were observed. This indicated that the isolates were either different or indicated a microevolutionary process of this microorganism

Keywords : Antifungal agents; Disk diffusion antimicrobial tests; Microbial sensitivity tests; Mycoses; Sporothrix; Sporotrichosis.

        · abstract in Portuguese     · text in English | Portuguese     · pdf in English | Portuguese