Anais Brasileiros de Dermatologia
Print version ISSN 0365-0596
BONAMIGO, Renan Rangel et al. HLA and skin cancer. An. Bras. Dermatol. [online]. 2012, vol.87, n.1, pp.9-18. ISSN 0365-0596. http://dx.doi.org/10.1590/S0365-05962012000100001.
Skin cancer - melanoma and non melanoma - are common neoplasm with rising incidence over the last decades. It is an important public health problem. Its pathogenesis is not completely understood and the same happens with the genetic factors involved. The genes that encode the HLA are associated with some tumors and they may be responsible for one of the mechanisms that take part in the development of the before mentioned cancers. We have reviewed the literature on the subject of HLA antigens, melanoma and non melanoma skin cancer.
Keywords : Carcinoma, basal cell; Carcinoma, squamous cell; HLA antigens; Melanoma; Neoplasms, basal cell; Skin neoplasms.