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Anais Brasileiros de Dermatologia

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ALMEIDA JR, Hiram Larangeira de; NUDELMANN, Lísia; ROCHA, Nara Moreira  and  CASTRO, Luis Antonio Suita de. Light and transmission electron microscopy of generalized dystrophic epidermolysis bullosa (Pasini's albopapuloid subtype). An. Bras. Dermatol. [online]. 2012, vol.87, n.2, pp.285-287. ISSN 0365-0596.

Pasini's albopapuloid epidermolysis bullosa is a very rare subtype of generalized dystrophic dominant epidermolyis bullosa. A 30 year-old white female patient presented since her childhood disseminated small blisters and papules. Light microscopy of a blister showed dermal-epidermal cleavage; moreover, focal areas of dermal-epidermal splitting were also observed. Transmission electron microscopy also identified focal areas of cleavage, which were seen below the lamina densa. It is important to recognize this condition as a variant of epidermolysis bullosa, since the most important cutaneous findings are generalized papules and not blisters and erosions as in other forms of epidermolysis bullosa.

Keywords : Epidermolysis bullosa dystrophica; Epidermolysis bullosa, junctional; Epidermolysis bullosa simplex; Histology; Microscopy, electron, transmission.

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