Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
KASSUGA, Luiza Erthal de Britto Pereira et al. Fox-Fordyce disease: response to adapalene 0.1%. An. Bras. Dermatol. [online]. 2012, vol.87, n.2, pp.329-331. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962012000200029.
The Fox-Fordyce disease is a rare inflammatory dermatosis that affects mainly young women and is characterized by multiple follicular papules, skin color or brownish, very itchy, localized in areas rich in apocrine glands. Histopathology shows focal spongiosis of the upper infundibulum with fibrosis and perifollicular lymphohistiocytic infiltrate. The diagnosis is based on clinical and histopathological examination. Many treatment options have been described; however none of them is excellent. We chose the topic adapalene 0.1% and a satisfactory improvement of the signs and symptoms of the disease was observed.
Keywords : Apocrine glands; Fox-Fordyce disease; Retinoids; Treatment outcome.