Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
DORTAS JUNIOR, Sergio Duarte et al. Prevalence of autoantibodies in a group of hereditary angioedema patients. An. Bras. Dermatol. [online]. 2012, vol.87, n.2, pp.332-334. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962012000200030.
Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patients with Hereditary Angioedema attended at Clementino Fraga Filho University Hospital accepted to participate in this study. Prevalence of AAB was 40%. Our data indicate high prevalence of AAB in patients with Hereditary Angioedema. Large-scale studies should be considered to determine the significance of these AAB in the follow-up care of patients with Hereditary Angioedema.
Keywords : Angioedemas, hereditary; Autoantibodies; Hereditary angioedema type III; Hereditary angioedema types I and II; Prevalence.