SciELO - Scientific Electronic Library Online

 
vol.87 issue2Fox-Fordyce disease: response to adapalene 0.1%Spontaneous involution of keratoacanthoma, iconographic documentation and similarity with volcanoes of nature author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596

Abstract

DORTAS JUNIOR, Sergio Duarte et al. Prevalence of autoantibodies in a group of hereditary angioedema patients. An. Bras. Dermatol. [online]. 2012, vol.87, n.2, pp. 332-334. ISSN 0365-0596.  http://dx.doi.org/10.1590/S0365-05962012000200030.

Hereditary Angioedema is a dominantly inherited disease. Routine screening of autoantibodies (AAB) is not recommended for individuals with Hereditary Angioedema; however, prevalence of these antibodies in Hereditary Angioedema patients is not well documented. We aim to determine the prevalence of AAB so that individuals at risk of developing autoimmune diseases can be identified. Fifteen patients with Hereditary Angioedema attended at Clementino Fraga Filho University Hospital accepted to participate in this study. Prevalence of AAB was 40%. Our data indicate high prevalence of AAB in patients with Hereditary Angioedema. Large-scale studies should be considered to determine the significance of these AAB in the follow-up care of patients with Hereditary Angioedema.

Keywords : Angioedemas, hereditary; Autoantibodies; Hereditary angioedema type III; Hereditary angioedema types I and II; Prevalence.

        · abstract in Portuguese     · text in English     · pdf in English