Anais Brasileiros de Dermatologia
On-line version ISSN 1806-4841
FREY, Marcos Noronha et al. Congenital and neonatal lupus erythematosus: two case reports. An. Bras. Dermatol. [online]. 2012, vol.87, n.4, pp.625-628. ISSN 1806-4841. http://dx.doi.org/10.1590/S0365-05962012000400019.
Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen antibodies through the placenta. At the moment of the diagnosis, the mothers are asymptomatic in 40 to 60% of cases. The most common manifestations are cutaneous lesions and congenital heart block. The cutaneous findings are variable and usually begin within the first weeks or months of life. Congenital lupus erythematosus is a congenital variant of neonatal lupus erythematosus. We present one case of congenital lupus erythematosus and one case of neonatal lupus erythematous, showing the variability of this disease.
Keywords : Congenital, hereditary, and neonatal diseases and abnormalities; Infant, newborn; Lupus erythematosus, cutaneous.