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Sarcoidosis and chronic hepatitis C: treatment with prednisone and colchicine* * Work performed at the Dermatology Service of Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro (HUGG - UNIRIO) – Rio de Janeiro (RJ), Brazil.

Abstract

Sarcoidosis is a disease which still has uncertain etiology. Possible environmental causes are cited in the literature, like organic and inorganic particles and infectious agents. Recent studies have demonstrated the occurrence of sarcoidosis in patients with chronic C hepatitis; however, this association remains without statistical or causal evidence. In this report a case of sarcoidosis associated with chronic hepatitis C will be described, with subcutaneous lesions, considered rare, and good response to treatment with colchicine and prednisone. The hepatitis C virus was isolated in sarcoid tissue and the association between the two diseases will be discussed.

Keywords:
Giant cells; Hepatitis C, chronic; Sarcoidosis; Skin abnormalities

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