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Anais Brasileiros de Dermatologia

Print version ISSN 0365-0596On-line version ISSN 1806-4841


FERNANDES, Karina de Almeida Pinto et al. Linear IgA and IgG bullous dermatosis. An. Bras. Dermatol. [online]. 2016, vol.91, n.5, suppl.1, pp.32-34. ISSN 0365-0596.

Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be considered a subtype of this dermatosis or a new entity. Further studies are needed to recognize this clinical variant.

Keywords : Basement membrane; Immunoglobulin A; Linear IgA bullous dermatosis.

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