Abstract

LAMBACK, Elisa Baranski; RESENDE, Fernanda Simões Seabra  and  LENZI, Thiara Cristina Rocha. Eosinophilic fasciitis. An. Bras. Dermatol. [online]. 2016, vol.91, n.5, suppl.1, pp.57-59. ISSN 0365-0596.  http://dx.doi.org/10.1590/abd1806-4841.20164683.

Eosinophilic fasciitis is a rare sclerodermiform syndrome of unknown etiology. It is characterized by the thickening of the muscular fascia and subcutaneous tissue, with a variable infiltration of eosinophils. Peripheral eosinophilia, poly or monoclonal hypergammaglobulinemia and increased erythrocyte sedimentation rate can be seen. Clinical features begin acutely, with local edema and a painful and symmetrical stiffening of the limbs, progressing rapidly to fibrosis, which can limit joint movements. Some cases have a history of strenuous physical exercise or trauma. The diagnosis is confirmed by a deep skin biopsy. Glucocorticoids in high doses is the treatment of choice. We report a typical eosinophilic fasciitis case with peripheral eosinophilia and dramatic response to pulse therapy with methylprednisolone.

Keywords : eosinophilia; fasciitis; fibrosis.

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