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Incapacitating solar urticaria: successful treatment with omalizumab* * Work conducted at the Department of Dermatology, Centro Hospitalar de Leiria, Leiria, Portugal.

Abstract:

Solar urticaria is a rare form of physical urticaria mediated by immunoglobulin E. The lesions appear immediately after the sun exposure, interfering with the patient's normal daily life. Omalizumab, a monoclonal anti-IgE antibody, has been recently approved for the treatment of chronic spontaneous urticaria, and the latest reports support its role also in the treatment of solar urticaria. Hereby, we report a case of solar urticaria refractory to conventional treatment strategies, with an excellent response to treatment with omalizumab and phototesting normalization.

Keywords:
Immunoglobulin E; Light; Photosensitivity disorders; Urticaria

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