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Multisystemic fusariosis with fulminant evolution How to cite this article: Turra N, Acosta A, Incoronato A, Beltramo P. Multisystemic fusariosis with fulminant evolution. An Bras Dermatol. 2020. https://doi.org/10.1016/j.abd.2020.03.007 ,☆☆ ☆☆ Study conducted at the Pereira Rossell Hospital, Montevideo, Uruguay.

Abstract

This report presents the case of a 13-year-old female patient with history of acute myeloid leukemia, who, after a bone marrow transplant, began to vomit and experienced rapidly progressive deterioration of consciousness, in addition to disseminated erythematous-violaceous macules, and some blisters with hemorrhagic content inside. Skin biopsy evidenced intravascular filamentous structures. A blood culture confirmed the presence of Fusarium oxysporum. Intravenous treatment with voriconazole was initiated. The patient evolved unfavorably with multiple necrotic skin lesions, ischemic brain lesions, and death.

KEYWORDS
Bacterial infections and mycoses; Bone marrow transplantation; Central nervous system fungal infections; Fusariosis; Fusarium

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