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Revista Brasileira de Reumatologia
On-line version ISSN 1809-4570
REZENDE, Marcelo Cruz; MAIA, Arlete Delfina Marques and HORIMOTO, Alex Magno Coelho. Post-chemotherapy rheumatism: an immunological tolerance dysfunction?. Rev. Bras. Reumatol. [online]. 2005, vol.45, n.1, pp.43-46. ISSN 1809-4570. http://dx.doi.org/10.1590/S0482-50042005000100009.
Post-chemotherapy rheumatism is a rare syndrome characterised by polyarthralgia that develops following a period of 1 to 4 months of various forms of chemotherapy for cancer treatment. There is very little representation of post-chemotherapy rheumatism (PCR) in literature. Here we report the case of a 21 years old girl with Hodgkin lymphoma who was not treated with cyclophosphamide, the drug considered as an etiological factor in PCR. Rather, we suggest the possibility of a transitory dysfunction in immunological tolerance mechanisms.
Keywords : post-chemotherapy rheumatism; Hodgkin's lymphoma; immunological tolerance.