SciELO - Scientific Electronic Library Online

 
vol.16 issue3Hemiarthroplasty for treatment of four part fracture -dislocation of the proximal humerus: grade of mobility related to age author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Acta Ortopédica Brasileira

Print version ISSN 1413-7852

Abstract

LEMOS, Sandro Pinheiro de Souza et al. Glycerol-preserved allogenous nerve: an experimental study with rats. Acta ortop. bras. [online]. 2008, vol.16, n.3, pp. 133-137. ISSN 1413-7852.  http://dx.doi.org/10.1590/S1413-78522008000300001.

The use of glycerol-preserved nerve allograft is an alternative to autografting in cases of peripheral nerve injury with loss of substance, which decreases surgical morbidity and provides sufficient material for neural repair. The objective of this study was to compare the degree of nervous repair, through interposition of autogenous graft (Group A), of glycerol-preserved vein tube (Group B), and interposition of glycerol-preserved allogenic nerve (Group C) in 5-mm defects of Wistar rats' fibular nerve, using histological and functional analyses. In group A (autograft) a perineural tissue reaction and myelinated axonal fibers escape out of the epineurium boundaries were greater when compared to those observed in Group B (autogenous vein + glycerol) and Group C (nerve allograft). The functional evaluation was made by analysis of the patterns of rats' posterior footprints (Walking Track Analysis) in preoperative, early postoperative period, week 3 and week 6. Regarding functional recovery, in none of the evaluated periods was there a statistically significant difference between the three groups.

Keywords : Transplant; Nervous regeneration; Glycerol; Fibular nerve; Wistar rats; Surgery [methods].

        · abstract in Portuguese     · text in English | Portuguese     · pdf in English | Portuguese