Abstract

NEVES, Lais Mara Siqueira das; MARCOLINO, Alexandre Marcio; PRADO, Rodrigo Paschoal  and  THOMAZINI, José Antônio. Laser 830nm on the viability of skin flaps in rats submitted of nicotine. Acta ortop. bras. [online]. 2011, vol.19, n.6, pp. 342-345. ISSN 1413-7852.  http://dx.doi.org/10.1590/S1413-78522011000600004.

OBJECTIVE: To investigate the possible effects of laser diode 830nm counter to the action of nicotine on the viability of the skin flap in rats. METHODS: 24 Wistar-albino rats were used, divided into 3 groups of 8: Group 1 - subject to the surgical technique to obtain the random skin flap in cranial base, subcutaneous injection of nicotine of 2mg/Kg/dia a week before and one week after surgery and simulation of laser. Group 2 - similar to group 1, the random skin flap in the cranial base were subjected to laser irradiation immediately after surgery and on thesubsequent 4 days. After euthanasia, areas of necrosis and viable tissue were examined by a manual method (weighing the Role of Feedback) and by the semi-automated method of analysis (Mini-Mop^®). RESULTS: The results were statistically analyzed by ANOVA. The values of the percentage of necrotic area by the method of analysis showed a decreased area of necrosis in group 2 where the laser was applied. CONCLUSION: The 830nm laser was effective in improving the viability of skin flaps in rats subjected to the action of nicotine. Level of evidence II: Therapeutic Studies - Investigating the results of treatment.

Keywords : Laser therapy; low-level; Surgical flaps; Nicotine; Necrosis; Reconstructive Surgical Procedures.