Brazilian Journal of Infectious Diseases
versión On-line ISSN 1678-4391
PINTO, Ana Yecê das Neves; VALENTE, Sebastião Aldo da Silva y VALENTE, Vera da Costa. Emerging acute Chagas Disease in Amazonian Brazil: case reports with serious cardiac involvement. Braz J Infect Dis [online]. 2004, vol.8, n.6, pp. 454-460. ISSN 1678-4391. http://dx.doi.org/10.1590/S1413-86702004000600010.
Four cases of serious cardiac attacks by autochthonous Trypanosoma cruzi infection from the Brazilian Amazon are reported; three of them occurred in micro-epidemic episodes. The manifestations included sudden fever, myalgia, dyspnea and signs of heart failure. Diagnosis was confirmed by specific exams, especially QBC (Quantitative Buffy Coat) and natural xenodiagnosis. Despite treatment with benznidazol, three patients died with serious myocarditis, renal failure and cardiac tamponade. The authors call attention to the emergence of this disease and reveal a previously unknown pathogenicity of T. cruzi strains in this area, added to a non-usual transmission form.
Palabras clave : Chagas disease; trypanosomiasis; cardiovascular; Brazilian Amazon; myocarditis.