Brazilian Journal of Infectious Diseases
Print version ISSN 1413-8670
HAZUDA, Daria J. Resistance to inhibitors of the human immunodeficiency virus type 1 integration. Braz J Infect Dis [online]. 2010, vol.14, n.5, pp. 513-518. ISSN 1413-8670. http://dx.doi.org/10.1590/S1413-86702010000500016.
This review will summarize the role of integrase in HIV-1 infection, the mechanism of integrase inhibitors and resistance with an emphasis on raltegravir (RAL), the first integrase inhibitor licensed to treat HIV-1 infection
Keywords : antiretrovirals; integrase inhibitors; raltegravir.